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A 48-year-old white woman presented with the chief complaint of worsening of facial hirsutism during a period of 6 months. Her history was remarkable for type 2 diabetes mellitus, hypertension, hypokalemia, and weight gain. All these conditions were diagnosed within approximately a 1-year period. Re...

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Veröffentlicht in:Endocrine practice 2005-09, Vol.11 (5), p.351
Hauptverfasser: Tanwani, Lal K., Mokshagundam, SriPrakash L.
Format: Artikel
Sprache:eng
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Zusammenfassung:A 48-year-old white woman presented with the chief complaint of worsening of facial hirsutism during a period of 6 months. Her history was remarkable for type 2 diabetes mellitus, hypertension, hypokalemia, and weight gain. All these conditions were diagnosed within approximately a 1-year period. Review of systems was remarkable for intermittent headaches and proximal muscle weakness. The patient is currently receiving corticosteroid replacement therapy. The failure to detect hormone-secreting pituitary microadenomas by MRI often results in invasive procedures, such as inferior petrosal sinus sampling (IPSS), to confirm the diagnosis. Dynamic contrast-enhanced MRI may eliminate the need for IPSS to confirm the diagnosis of ACTH-secreting pituitary microadenomas in some cases.
ISSN:1530-891X
1934-2403
DOI:10.4158/EP.11.5.351