Combined Chondroitin sulfate and Glucosamine is more efficient than Celebrex in reducing serum levels of COLL2-1, a cartilage degradation biomarker, in patients with severe OA: results from a randomized, double-blind, multicentric clinical trial

Combined Chondroitin sulfate and Glucosamine is more efficient than Celebrex in reducing serum levels of COLL2-1, a cartilage degradation biomarker, in patients with severe OA: results from a randomized, double-blind, multicentric clinical trial

The objective of the study was to investigate soluble osteoarthritis (OA) biomarkers in the patients of the double-blind Multicentre Osteoarthritis interVEntion trial with Sysadoa (MOVES) comparing the symptomatic efficacy and safety of Chondroitin Sulfate (CS)+Glucosamine Hydrochloride (GH) versus...

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Veröffentlicht in:Clinical therapeutics 2015-08, Vol.37 (8), p.e121-e122
Hauptverfasser: Henrotin, Y, Arden, N, Berenbaum, F, Blanco, F.J, Castillo, J.R, Conaghan, P.G, Hick, A.C, Hochberg, M.C, Martel-Pelletier, J, Monfort, J, Möller, I, Pap, T, Pelletier, J.-P, Richette, P, Sawitzke, A.D, du Souich, P
Format: Artikel
Sprache:eng
Schlagworte:
Biomarkers
Chondroitin sulfate
Internal Medicine
Medical Education
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Zusammenfassung:The objective of the study was to investigate soluble osteoarthritis (OA) biomarkers in the patients of the double-blind Multicentre Osteoarthritis interVEntion trial with Sysadoa (MOVES) comparing the symptomatic efficacy and safety of Chondroitin Sulfate (CS)+Glucosamine Hydrochloride (GH) versus CElecoxib (CE) in knee OA patients.
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2015.05.347