Fenofibrate Improves the Impaired Endothelial Progenitor Cell Function Through Deregulating Nalp3 Inflammasome Activity In Diabetic Mice

Fenofibrate Improves the Impaired Endothelial Progenitor Cell Function Through Deregulating Nalp3 Inflammasome Activity In Diabetic Mice

The current study aimed to test our hypothesis that fenofibrate improves angiogenesis and restore endothelial progenitor cell (EPC) function via deregulating NALP3 inflammasome activity in streptozotocin (STZ)-induced diabetic mice.

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Veröffentlicht in:Clinical therapeutics 2015-08, Vol.37 (8), p.e25-e25
Hauptverfasser: Deng, Y.-P, Zhao, T, Huang, F, Ni, M, Li, D.-J, Jiang, G.-J, Shen, F.-M
Format: Artikel
Sprache:eng
Schlagworte:
Amputation
Diabetes
Internal Medicine
Medical Education
Rodents
Wound healing
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Zusammenfassung:The current study aimed to test our hypothesis that fenofibrate improves angiogenesis and restore endothelial progenitor cell (EPC) function via deregulating NALP3 inflammasome activity in streptozotocin (STZ)-induced diabetic mice.
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2015.05.079