CD147, The Ancillary protein of MCT4, as marker for prognosis and clinical outcome in primary clear cell renal cell Carcinoma and Metastasis

Just as previously demonstrated for MCT4, CD147 is proposed to be associated with tumor progression and metastasis in clear cell renal cell carcinoma (ccRCC) and therefore might represent a promising target for therapeutic intervention and a marker for prognosis and patient outcome.

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Veröffentlicht in:Clinical therapeutics 2015-08, Vol.37 (8), p.e75-e76
Hauptverfasser: Fisel, P, Stühler, V, Winter, S, Rausch, S, Hennenlotter, J, Nies, A.T, Stenzl, A, Scharpf, M, Fend, F, Kruck, S, Bedke, J, Schwab, M, Schaeffeler, E
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Sprache:eng
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Zusammenfassung:Just as previously demonstrated for MCT4, CD147 is proposed to be associated with tumor progression and metastasis in clear cell renal cell carcinoma (ccRCC) and therefore might represent a promising target for therapeutic intervention and a marker for prognosis and patient outcome.
ISSN:0149-2918
1879-114X
DOI:10.1016/j.clinthera.2015.05.218