Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma

Impaired JNK signaling cooperates with KrasG12D expression to accelerate pancreatic ductal adenocarcinoma

[...]we examined the cooperative interaction between pancreas-specific mkk4/mkk7 gene deletion and oncogenic activation of Kras to increase our molecular understanding by which activated Kras contributes to pancreatic cancer.

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Bibliographische Detailangaben
Veröffentlicht in:Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2015-06, Vol.15 (3), p.S36-S36
Hauptverfasser: Tournier, Cathy, Davies, Clare C, Harvey, Emma, McMahon, Raymond F.T, Finegan, Katherine G, Connor, Frances, Davis, Roger J, Tuveson, David A
Format: Artikel
Sprache:eng
Schlagworte:
Endocrinology & Metabolism
Gastroenterology and Hepatology
Kinases
Pancreas
Rodents
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Zusammenfassung:[...]we examined the cooperative interaction between pancreas-specific mkk4/mkk7 gene deletion and oncogenic activation of Kras to increase our molecular understanding by which activated Kras contributes to pancreatic cancer.
ISSN:1424-3903
1424-3911
DOI:10.1016/j.pan.2015.05.156