Papillary carcinoma of the thyroid with manifestations resembling Graves' disease
To describe a case of papillary carcinoma of the thyroid that mimicked a diffuse toxic goiter. We present a detailed case report, review related cases in the literature, and discuss the possible role of autoantibodies in promoting the growth of papillary thyroid tumor. A 28-year-old woman had a 6-mo...
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Veröffentlicht in: | Endocrine practice 2001-03, Vol.7 (2), p.106-109 |
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Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | To describe a case of papillary carcinoma of the thyroid that mimicked a diffuse toxic goiter.
We present a detailed case report, review related cases in the literature, and discuss the possible role of autoantibodies in promoting the growth of papillary thyroid tumor.
A 28-year-old woman had a 6-month history of weight loss, palpitations, increased anxiety, and enlargement of her thyroid gland. Laboratory studies confirmed the presence of hyperthyroidism. A 1-cm nodule was identified at the left upper pole of the thyroid. Fine-needle aspiration biopsy of this nodule revealed papillary carcinoma of the thyroid. Total thyroidectomy and a modified radical neck dissection were performed. Microscopic examination showed that the entire gland was replaced by a papillary carcinoma with a predominantly follicular pattern of growth. Of 44 lymph nodes tested, 31 were positive for metastatic papillary thyroid carcinoma. The presence of thyroid antibodies may have had a role in the aggressiveness of the patient's disease.
To our knowledge, this is the first published report of a papillary thyroid cancer with manifestations resembling Graves' disease. |
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ISSN: | 1530-891X 1934-2403 |
DOI: | 10.4158/ep.7.2.106 |