ChemInform Abstract: A General, Enantioselective Synthesis of N-Alkyl Terminal Aziridines and C2-Functionalized Azetidines via Organocatalysis

Enantioselective α‐chlorination of aldehydes (V) provides chlorides (I) which are converted into nitriles followed by intramolecular cyclization to azetidines (IV).

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	ChemInform 2015-06, Vol.46 (26), p.no-no
Hauptverfasser:	Senter, Timothy J., O'Reilly, Matthew C., Chong, Katherine M., Sulikowski, Gary A., Lindsley, Craig W.
Format:	Artikel
Sprache:	eng
Schlagworte:	azetidine derivatives aziridine derivatives diastereoselective syntheses diastereoselective syntheses, enantioselective syntheses (incl. cis/trans‐isomerism) enantioselective syntheses (incl. cis/trans-isomerism) halogenation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Enantioselective α‐chlorination of aldehydes (V) provides chlorides (I) which are converted into nitriles followed by intramolecular cyclization to azetidines (IV).
ISSN:	0931-7597 1522-2667
DOI:	10.1002/chin.201526128