IrSPI, a Tick Serine Protease Inhibitor Involved in Tick Feeding and Bartonella henselae Infection: e2993

IrSPI, a Tick Serine Protease Inhibitor Involved in Tick Feeding and Bartonella henselae Infection: e2993

Abstract Ixodes ricinus is the most widespread and abundant tick in Europe, frequently bites humans, and is the vector of several pathogens including those responsible for Lyme disease, Tick-Borne Encephalitis, anaplasmosis, babesiosis and bartonellosis. Expression patterns of five selected genes be...

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Veröffentlicht in:PLoS neglected tropical diseases 2014-07, Vol.8 (7)
Hauptverfasser: Liu, Xiang Ye, Fuente, Jose dela, Cote, Martine, Galindo, Ruth C, Moutailler, Sara, Vayssier-Taussat, Muriel, Bonnet, Sarah I
Format: Artikel
Sprache:eng
Schlagworte:
Arachnids
Bacteria
Bacterial infections
Encephalitis
Gene expression
Infections
Lyme disease
Parasitic diseases
Proteinase inhibitors
Tropical diseases
Vector-borne diseases
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Zusammenfassung:Abstract Ixodes ricinus is the most widespread and abundant tick in Europe, frequently bites humans, and is the vector of several pathogens including those responsible for Lyme disease, Tick-Borne Encephalitis, anaplasmosis, babesiosis and bartonellosis. Expression patterns of five selected genes belonging to the BPTI/Kunitz family of serine protease inhibitors, the tick salivary peptide group 1 protein, the salp15 super-family, and the arthropod defensin family, were validated by qRT-PCR.
ISSN:1935-2727
1935-2735
DOI:10.1371/journal.pntd.0002993