ChemInform Abstract: Synthesis of 3-Acetyl-4-hydroxy-1-phenylpyridin-2(1H)-one Derivatives

ChemInform Abstract: Synthesis of 3-Acetyl-4-hydroxy-1-phenylpyridin-2(1H)-one Derivatives

Reaction of azomethines (I) with two equivalents of malonates provides access to pyranopyridinediones (III), which suffer a ring opening in alkaline diglycol to furnish the title pyridine derivatives (IV) in high yields.

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Veröffentlicht in:ChemInform 2015-06, Vol.46 (24), p.no-no
Hauptverfasser: Nikam, B. P., Kappe, T.
Format: Artikel
Sprache:eng
Schlagworte:
annulation reactions
pyridine derivatives
ring closure reactions
ring closure reactions, annulation reactions
ring opening reactions
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Beschreibung
Zusammenfassung:Reaction of azomethines (I) with two equivalents of malonates provides access to pyranopyridinediones (III), which suffer a ring opening in alkaline diglycol to furnish the title pyridine derivatives (IV) in high yields.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201524169