DAMAGING CARDIAC GENE VARIANTS DETERMINE RESPONSE TO LVAD THERAPY

Only 1 of the 10 patients with damaging cardiac gene variants improved their ejection fraction to greater than 45% post LVAD. 4 of the 5 patients without mutations improved their ejection fraction to greater than 45%, p-value=.03 Conclusion: Damaging cardiac gene variants are common in this populati...

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Veröffentlicht in:Journal of the American College of Cardiology 2015-03, Vol.65 (10), p.A891-A891
Hauptverfasser: Rome, Eric, Dhar, Kajari, Moulton, Alexandra, Zhao, Junhan, Kittrell, Jeff, Eudy, James, Raichlin, Eugenia, Um, John, Moulton, Michael, Thiele, Geoffrey, Redder, Ronald, Anderson, Daniel, Lowes, Brian
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container_end_page A891
container_issue 10
container_start_page A891
container_title Journal of the American College of Cardiology
container_volume 65
creator Rome, Eric
Dhar, Kajari
Moulton, Alexandra
Zhao, Junhan
Kittrell, Jeff
Eudy, James
Raichlin, Eugenia
Um, John
Moulton, Michael
Thiele, Geoffrey
Redder, Ronald
Anderson, Daniel
Lowes, Brian
description Only 1 of the 10 patients with damaging cardiac gene variants improved their ejection fraction to greater than 45% post LVAD. 4 of the 5 patients without mutations improved their ejection fraction to greater than 45%, p-value=.03 Conclusion: Damaging cardiac gene variants are common in this population.
doi_str_mv 10.1016/S0735-1097(15)60891-9
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source Elsevier ScienceDirect Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection
subjects Cardiology
Cardiomyopathy
Deoxyribonucleic acid
DNA
Genes
title DAMAGING CARDIAC GENE VARIANTS DETERMINE RESPONSE TO LVAD THERAPY
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