DAMAGING CARDIAC GENE VARIANTS DETERMINE RESPONSE TO LVAD THERAPY

DAMAGING CARDIAC GENE VARIANTS DETERMINE RESPONSE TO LVAD THERAPY

Only 1 of the 10 patients with damaging cardiac gene variants improved their ejection fraction to greater than 45% post LVAD. 4 of the 5 patients without mutations improved their ejection fraction to greater than 45%, p-value=.03 Conclusion: Damaging cardiac gene variants are common in this populati...

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Veröffentlicht in:Journal of the American College of Cardiology 2015-03, Vol.65 (10), p.A891-A891
Hauptverfasser: Rome, Eric, Dhar, Kajari, Moulton, Alexandra, Zhao, Junhan, Kittrell, Jeff, Eudy, James, Raichlin, Eugenia, Um, John, Moulton, Michael, Thiele, Geoffrey, Redder, Ronald, Anderson, Daniel, Lowes, Brian
Format: Artikel
Sprache:eng
Schlagworte:
Cardiology
Cardiomyopathy
Deoxyribonucleic acid
DNA
Genes
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Zusammenfassung:Only 1 of the 10 patients with damaging cardiac gene variants improved their ejection fraction to greater than 45% post LVAD. 4 of the 5 patients without mutations improved their ejection fraction to greater than 45%, p-value=.03 Conclusion: Damaging cardiac gene variants are common in this population.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(15)60891-9