INTRACORONARY CARDIOSPHERE–DERIVED CELLS (ICCDCS) PRODUCE MICROCIRCULATORY REMODELING BUT DO NOT INCREASE CORONARY FLOW RESERVE IN SWINE WITH HIBERNATING MYOCARDIUM

INTRACORONARY CARDIOSPHERE–DERIVED CELLS (ICCDCS) PRODUCE MICROCIRCULATORY REMODELING BUT DO NOT INCREASE CORONARY FLOW RESERVE IN SWINE WITH HIBERNATING MYOCARDIUM

Conclusion These data indicate that icCDCs stimulate capillary angiogenesis but normalize arteriolar density. [...]the functional improvement resulting from icCDCs is associated with microcirculatory remodeling but independent of an increase in collateral perfusion.

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Veröffentlicht in:Journal of the American College of Cardiology 2013-03, Vol.61 (10), p.E1822-E1822
Hauptverfasser: Kamouh, Abdallah, Weil, Brian, Leiker, Merced, Canty, John, Suzuki, Gen
Format: Artikel
Sprache:eng
Schlagworte:
Angiogenesis
Cardiology
Cardiovascular
Internal Medicine
Medical research
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Zusammenfassung:Conclusion These data indicate that icCDCs stimulate capillary angiogenesis but normalize arteriolar density. [...]the functional improvement resulting from icCDCs is associated with microcirculatory remodeling but independent of an increase in collateral perfusion.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(13)61822-7