ChemInform Abstract: Improved and Scalable Preparation of 6-Bromo-4-chlorothieno[2,3-d]pyrimidine

ChemInform Abstract: Improved and Scalable Preparation of 6-Bromo-4-chlorothieno[2,3-d]pyrimidine

The title compound (VII), a useful precursor for the synthesis of a library of thienopyrimidine‐based kinase inhibitors, is obtained starting from cheap bulk chemicals in four steps.

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Veröffentlicht in:ChemInform 2015-04, Vol.46 (16), p.no-no
Hauptverfasser: Bugge, S., Skjoensfjell, E. M., Willumsen, F. B., Sundby, E., Hoff, B. H.
Format: Artikel
Sprache:eng
Schlagworte:
annulation reactions
fused pyrimidine derivatives
ring closure reactions
ring closure reactions, annulation reactions
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Beschreibung
Zusammenfassung:The title compound (VII), a useful precursor for the synthesis of a library of thienopyrimidine‐based kinase inhibitors, is obtained starting from cheap bulk chemicals in four steps.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201516255