A case of respiratory depression in a child with ultrarapid CYP2D6 metabolism after tramadol
We discuss a case of severe respiratory depression in a child, with ultrarapid CYP2D6 genotype and obstructive sleep apnea syndrome, after taking tramadol for pain relief related to a day-case tonsillectomy.
Gespeichert in:
| Veröffentlicht in: | Pediatrics (Evanston) 2015-03, Vol.135 (3), p.e753-e755 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | e755 |
|---|---|
| container_issue | 3 |
| container_start_page | e753 |
| container_title | Pediatrics (Evanston) |
| container_volume | 135 |
| creator | Orliaguet, Gilles Hamza, Jamil Couloigner, Vincent Denoyelle, Françoise Loriot, Marie-Anne Broly, Franck Garabedian, Erea Noel |
| description | We discuss a case of severe respiratory depression in a child, with ultrarapid CYP2D6 genotype and obstructive sleep apnea syndrome, after taking tramadol for pain relief related to a day-case tonsillectomy. |
| doi_str_mv | 10.1542/peds.2014-2673 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_1661724728</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3619022881</sourcerecordid><originalsourceid>FETCH-LOGICAL-c388t-8069965b1d7de5120c015f9d1581025552649caeca94172438b73d96b80d63f3</originalsourceid><addsrcrecordid>eNo9kEtLw0AUhQdRbK1uXcqA69Q778my1CcUdNGNIAyTzIROSZo4kyL99ya0uroc-M658CF0S2BOBKcPnXdpToHwjErFztCUQK4zTpU4R1MARjIOICboKqUtAHCh6CWaUCG5kkpN0dcClzZ53FY4-tSFaPs2HrDz3RBTaHc47LDF5SbUDv-EfoP3dR9ttF1wePn5QR8lbnxvi7YOqcG26n3EA9BY19bX6KKydfI3pztD6-en9fI1W72_vC0Xq6xkWveZBpnnUhTEKecFoVACEVXuiNAEqBCCSp6X1pc250RRznShmMtlocFJVrEZuj_OdrH93vvUm227j7vhoyFSjg1F9UDNj1QZ25Sir0wXQ2PjwRAwo0szujSjSzO6HAp3p9l90Xj3j__JY7_P-G5b</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1661724728</pqid></control><display><type>article</type><title>A case of respiratory depression in a child with ultrarapid CYP2D6 metabolism after tramadol</title><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Alma/SFX Local Collection</source><creator>Orliaguet, Gilles ; Hamza, Jamil ; Couloigner, Vincent ; Denoyelle, Françoise ; Loriot, Marie-Anne ; Broly, Franck ; Garabedian, Erea Noel</creator><creatorcontrib>Orliaguet, Gilles ; Hamza, Jamil ; Couloigner, Vincent ; Denoyelle, Françoise ; Loriot, Marie-Anne ; Broly, Franck ; Garabedian, Erea Noel</creatorcontrib><description>We discuss a case of severe respiratory depression in a child, with ultrarapid CYP2D6 genotype and obstructive sleep apnea syndrome, after taking tramadol for pain relief related to a day-case tonsillectomy.</description><identifier>ISSN: 0031-4005</identifier><identifier>EISSN: 1098-4275</identifier><identifier>DOI: 10.1542/peds.2014-2673</identifier><identifier>PMID: 25647677</identifier><identifier>CODEN: PEDIAU</identifier><language>eng</language><publisher>United States: American Academy of Pediatrics</publisher><subject>Analgesics, Opioid - adverse effects ; Analgesics, Opioid - therapeutic use ; Child, Preschool ; Children & youth ; Cytochrome P-450 CYP2D6 - drug effects ; Cytochrome P-450 CYP2D6 - genetics ; Cytochrome P-450 CYP2D6 - metabolism ; Genotype ; Genotype & phenotype ; Humans ; Male ; Metabolism ; Narcotics ; Pain, Postoperative - drug therapy ; Pediatrics ; Respiratory diseases ; Respiratory Insufficiency - enzymology ; Respiratory Insufficiency - etiology ; Sleep apnea ; Tonsillectomy ; Tramadol - adverse effects ; Tramadol - therapeutic use</subject><ispartof>Pediatrics (Evanston), 2015-03, Vol.135 (3), p.e753-e755</ispartof><rights>Copyright © 2015 by the American Academy of Pediatrics.</rights><rights>Copyright American Academy of Pediatrics Mar 2015</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c388t-8069965b1d7de5120c015f9d1581025552649caeca94172438b73d96b80d63f3</citedby><cites>FETCH-LOGICAL-c388t-8069965b1d7de5120c015f9d1581025552649caeca94172438b73d96b80d63f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/25647677$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Orliaguet, Gilles</creatorcontrib><creatorcontrib>Hamza, Jamil</creatorcontrib><creatorcontrib>Couloigner, Vincent</creatorcontrib><creatorcontrib>Denoyelle, Françoise</creatorcontrib><creatorcontrib>Loriot, Marie-Anne</creatorcontrib><creatorcontrib>Broly, Franck</creatorcontrib><creatorcontrib>Garabedian, Erea Noel</creatorcontrib><title>A case of respiratory depression in a child with ultrarapid CYP2D6 metabolism after tramadol</title><title>Pediatrics (Evanston)</title><addtitle>Pediatrics</addtitle><description>We discuss a case of severe respiratory depression in a child, with ultrarapid CYP2D6 genotype and obstructive sleep apnea syndrome, after taking tramadol for pain relief related to a day-case tonsillectomy.</description><subject>Analgesics, Opioid - adverse effects</subject><subject>Analgesics, Opioid - therapeutic use</subject><subject>Child, Preschool</subject><subject>Children & youth</subject><subject>Cytochrome P-450 CYP2D6 - drug effects</subject><subject>Cytochrome P-450 CYP2D6 - genetics</subject><subject>Cytochrome P-450 CYP2D6 - metabolism</subject><subject>Genotype</subject><subject>Genotype & phenotype</subject><subject>Humans</subject><subject>Male</subject><subject>Metabolism</subject><subject>Narcotics</subject><subject>Pain, Postoperative - drug therapy</subject><subject>Pediatrics</subject><subject>Respiratory diseases</subject><subject>Respiratory Insufficiency - enzymology</subject><subject>Respiratory Insufficiency - etiology</subject><subject>Sleep apnea</subject><subject>Tonsillectomy</subject><subject>Tramadol - adverse effects</subject><subject>Tramadol - therapeutic use</subject><issn>0031-4005</issn><issn>1098-4275</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2015</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLw0AUhQdRbK1uXcqA69Q778my1CcUdNGNIAyTzIROSZo4kyL99ya0uroc-M658CF0S2BOBKcPnXdpToHwjErFztCUQK4zTpU4R1MARjIOICboKqUtAHCh6CWaUCG5kkpN0dcClzZ53FY4-tSFaPs2HrDz3RBTaHc47LDF5SbUDv-EfoP3dR9ttF1wePn5QR8lbnxvi7YOqcG26n3EA9BY19bX6KKydfI3pztD6-en9fI1W72_vC0Xq6xkWveZBpnnUhTEKecFoVACEVXuiNAEqBCCSp6X1pc250RRznShmMtlocFJVrEZuj_OdrH93vvUm227j7vhoyFSjg1F9UDNj1QZ25Sir0wXQ2PjwRAwo0szujSjSzO6HAp3p9l90Xj3j__JY7_P-G5b</recordid><startdate>20150301</startdate><enddate>20150301</enddate><creator>Orliaguet, Gilles</creator><creator>Hamza, Jamil</creator><creator>Couloigner, Vincent</creator><creator>Denoyelle, Françoise</creator><creator>Loriot, Marie-Anne</creator><creator>Broly, Franck</creator><creator>Garabedian, Erea Noel</creator><general>American Academy of Pediatrics</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TS</scope><scope>7U9</scope><scope>H94</scope><scope>K9.</scope><scope>M7N</scope><scope>NAPCQ</scope><scope>U9A</scope></search><sort><creationdate>20150301</creationdate><title>A case of respiratory depression in a child with ultrarapid CYP2D6 metabolism after tramadol</title><author>Orliaguet, Gilles ; Hamza, Jamil ; Couloigner, Vincent ; Denoyelle, Françoise ; Loriot, Marie-Anne ; Broly, Franck ; Garabedian, Erea Noel</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c388t-8069965b1d7de5120c015f9d1581025552649caeca94172438b73d96b80d63f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2015</creationdate><topic>Analgesics, Opioid - adverse effects</topic><topic>Analgesics, Opioid - therapeutic use</topic><topic>Child, Preschool</topic><topic>Children & youth</topic><topic>Cytochrome P-450 CYP2D6 - drug effects</topic><topic>Cytochrome P-450 CYP2D6 - genetics</topic><topic>Cytochrome P-450 CYP2D6 - metabolism</topic><topic>Genotype</topic><topic>Genotype & phenotype</topic><topic>Humans</topic><topic>Male</topic><topic>Metabolism</topic><topic>Narcotics</topic><topic>Pain, Postoperative - drug therapy</topic><topic>Pediatrics</topic><topic>Respiratory diseases</topic><topic>Respiratory Insufficiency - enzymology</topic><topic>Respiratory Insufficiency - etiology</topic><topic>Sleep apnea</topic><topic>Tonsillectomy</topic><topic>Tramadol - adverse effects</topic><topic>Tramadol - therapeutic use</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Orliaguet, Gilles</creatorcontrib><creatorcontrib>Hamza, Jamil</creatorcontrib><creatorcontrib>Couloigner, Vincent</creatorcontrib><creatorcontrib>Denoyelle, Françoise</creatorcontrib><creatorcontrib>Loriot, Marie-Anne</creatorcontrib><creatorcontrib>Broly, Franck</creatorcontrib><creatorcontrib>Garabedian, Erea Noel</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Physical Education Index</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Nursing & Allied Health Premium</collection><jtitle>Pediatrics (Evanston)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Orliaguet, Gilles</au><au>Hamza, Jamil</au><au>Couloigner, Vincent</au><au>Denoyelle, Françoise</au><au>Loriot, Marie-Anne</au><au>Broly, Franck</au><au>Garabedian, Erea Noel</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A case of respiratory depression in a child with ultrarapid CYP2D6 metabolism after tramadol</atitle><jtitle>Pediatrics (Evanston)</jtitle><addtitle>Pediatrics</addtitle><date>2015-03-01</date><risdate>2015</risdate><volume>135</volume><issue>3</issue><spage>e753</spage><epage>e755</epage><pages>e753-e755</pages><issn>0031-4005</issn><eissn>1098-4275</eissn><coden>PEDIAU</coden><abstract>We discuss a case of severe respiratory depression in a child, with ultrarapid CYP2D6 genotype and obstructive sleep apnea syndrome, after taking tramadol for pain relief related to a day-case tonsillectomy.</abstract><cop>United States</cop><pub>American Academy of Pediatrics</pub><pmid>25647677</pmid><doi>10.1542/peds.2014-2673</doi><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0031-4005 |
| ispartof | Pediatrics (Evanston), 2015-03, Vol.135 (3), p.e753-e755 |
| issn | 0031-4005 1098-4275 |
| language | eng |
| recordid | cdi_proquest_journals_1661724728 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Alma/SFX Local Collection |
| subjects | Analgesics, Opioid - adverse effects Analgesics, Opioid - therapeutic use Child, Preschool Children & youth Cytochrome P-450 CYP2D6 - drug effects Cytochrome P-450 CYP2D6 - genetics Cytochrome P-450 CYP2D6 - metabolism Genotype Genotype & phenotype Humans Male Metabolism Narcotics Pain, Postoperative - drug therapy Pediatrics Respiratory diseases Respiratory Insufficiency - enzymology Respiratory Insufficiency - etiology Sleep apnea Tonsillectomy Tramadol - adverse effects Tramadol - therapeutic use |
| title | A case of respiratory depression in a child with ultrarapid CYP2D6 metabolism after tramadol |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-21T21%3A05%3A08IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20case%20of%20respiratory%20depression%20in%20a%20child%20with%20ultrarapid%20CYP2D6%20metabolism%20after%20tramadol&rft.jtitle=Pediatrics%20(Evanston)&rft.au=Orliaguet,%20Gilles&rft.date=2015-03-01&rft.volume=135&rft.issue=3&rft.spage=e753&rft.epage=e755&rft.pages=e753-e755&rft.issn=0031-4005&rft.eissn=1098-4275&rft.coden=PEDIAU&rft_id=info:doi/10.1542/peds.2014-2673&rft_dat=%3Cproquest_cross%3E3619022881%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1661724728&rft_id=info:pmid/25647677&rfr_iscdi=true |