ChemInform Abstract: Synthesis of Arylsulfonyl-Quinones and Arylsulfonyl-1,4-diols as FabH Inhibitors: Pd-Catalyzed Direct C-Sulfone Formation by C-S Coupling of Quinones with Arylsulfonyl Chloride

A facile protocol is developed for the coupling of quinones with arysulfonyl chlorides to give arylsulfonyl quinones, which can be easily reduced to the corresponding 1,4‐diols.

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Bibliographische Detailangaben
Veröffentlicht in:	ChemInform 2015-03, Vol.46 (11), p.no-no
Hauptverfasser:	Ge, Bingyang, Wang, Dawei, Dong, Weifu, Ma, Piming, Li, Yongliang, Ding, Yuqiang
Format:	Artikel
Sprache:	eng
Schlagworte:	catalysis catalysis, phase‐transfer catalysis phase-transfer catalysis S-alkylation sulfenes and derivatives (benzene compounds) sulfonation sulfones sulfoxides sulfoxides, sulfones, sulfenes and derivatives (benzene compounds) sulfuration sulfuration, sulfonation, S‐alkylation
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Beschreibung
Zusammenfassung:	A facile protocol is developed for the coupling of quinones with arysulfonyl chlorides to give arylsulfonyl quinones, which can be easily reduced to the corresponding 1,4‐diols.
ISSN:	0931-7597 1522-2667
DOI:	10.1002/chin.201511106