Improved synthesis of 6-[(ethylthio)methyl]-1 H -indazole
In the improved synthesis of 6-[(ethylthio)methyl]-1 H -indazole ( 5 ), the mesylate intermediate is replaced by the bromide derivative, which increases the overall yield (six steps) by a factor of 3.
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| Veröffentlicht in: | Heterocyclic communications 2015-02, Vol.21 (1), p.5-8 |
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| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
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| Zusammenfassung: | In the improved synthesis of 6-[(ethylthio)methyl]-1
H
-indazole (
5
), the mesylate intermediate is replaced by the bromide derivative, which increases the overall yield (six steps) by a factor of 3. |
|---|---|
| ISSN: | 0793-0283 2191-0197 |
| DOI: | 10.1515/hc-2014-0180 |