Etude phytochimique, activités antiradicalaire, antibactérienne et antifongique d'extraits de Sebastiania chamaelea (L.) Müll.Arg/Phytochemical study, antioxidant, antibacterial and antifungal activities of Sebastiania chamaelea extracts (L.) Müll.Arg

Sebastiania chamaelea (L.), Müll.Arg is a shrub from the Euphorbiaceae family, which phytochemical screening revealed the presence of tannins, polyphenols, flavonoids, triterpenes, steroids and signs of quinones compounds. Polyphenolics' compounds dosage showed an abundance of phenolic acids in...

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Veröffentlicht in:Journal de la Société ouest-africaine de chimie 2014-07, Vol.37, p.10
Hauptverfasser: Mamadou, Roumanatou Sadou, Moussa, Idrissa, Sessou, Philippe, Yehouenou, Boniface, Agbangnan, Pascal D C, Illagouma, Amadou Tidjani, Abdoulaye, Alassane, Sohounhloué, Dominique C K, Ikhiri, Khalid
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Zusammenfassung:Sebastiania chamaelea (L.), Müll.Arg is a shrub from the Euphorbiaceae family, which phytochemical screening revealed the presence of tannins, polyphenols, flavonoids, triterpenes, steroids and signs of quinones compounds. Polyphenolics' compounds dosage showed an abundance of phenolic acids in the plant's aqueous extract and flavonoids in the ethanol extract of its areal parts. These extracts were tested for their antioxidant activity, antibacterial activity on Staphylococcus aureus ATCC25923 and Escherichia coli ATCC25922, and antifungal activity on Candida albicans ATCC10231. The ethanolic extract showed the best results, with an antioxidant activity (IC^sub 50^=7,5μg/ml) twice higher than the aquaeous extract's one (IC^sub 50^=15μg/ml). Furthermore, it showed the best antimicrobial activity on S. aureus with an inhibition of bacterial growth of 14,00 ± 1,70mm, an MIC of 3,12mg/ml and an MBC of 12,50mg/ml. These results can justify traditional uses of S. chamaelea in the treatment of certain bacterial diseases.
ISSN:0796-6687