ChemInform Abstract: Synthesis of Trifluoromethyl-Substituted 3-Azabicyclo[n.1.0]alkanes: Advanced Building Blocks for Drug Discovery

ChemInform Abstract: Synthesis of Trifluoromethyl-Substituted 3-Azabicyclo[n.1.0]alkanes: Advanced Building Blocks for Drug Discovery

Title compounds are prepared by CuCl‐mediated trifluoromethylcyclopropanation of cyclic enamides (I), (VI), and (IX) with CF3‐CHN2.

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Veröffentlicht in:ChemInform 2015-02, Vol.46 (7), p.no-no
Hauptverfasser: Artamonov, Olexiy S., Slobodyanyuk, Evgeniy Y., Volochnyuk, Dmitriy M., Komarov, Igor V., Tolmachev, Andrey A., Mykhailiuk, Pavel K.
Format: Artikel
Sprache:eng
Schlagworte:
cyclopropanation reactions
fused pyridine derivatives
fused pyrrole derivatives
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Zusammenfassung:Title compounds are prepared by CuCl‐mediated trifluoromethylcyclopropanation of cyclic enamides (I), (VI), and (IX) with CF3‐CHN2.
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201507037