ChemInform Abstract: Synthesis of New Class of Spirocarbocycle Derivatives by Multicomponent Domino Reaction and Their Evaluation for Antimicrobial, Anticancer Activity and Molecular Docking Studies

A series of 25 new spirocarbocycles such as (IV), (VI), (VIII) is synthesized including three derivatives (VI) and (VIIId) showing good anticancer activities against A549 cancer cell line.

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Bibliographische Detailangaben
Veröffentlicht in:	ChemInform 2015-01, Vol.46 (3), p.no-no
Hauptverfasser:	Sudhapriya, N., Perumal, P. T., Balachandran, C., Ignacimuthu, S., Sangeetha, M., Doble, Mukesh
Format:	Artikel
Sprache:	eng
Schlagworte:	annulation reactions antibacterial activity antibacterial activity, antimicrobial activity, antiprotozoal activity anticancer activity anticarcinogenic activity anticarcinogenic activity, anticancer activity antimicrobial activity antiprotozoal activity Berries cascade reactions cascade reactions, domino reactions, tandem reactions domino reactions ring closure reactions ring closure reactions, annulation reactions spirocyclic compounds (isocyclic compounds) tandem reactions
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Beschreibung
Zusammenfassung:	A series of 25 new spirocarbocycles such as (IV), (VI), (VIII) is synthesized including three derivatives (VI) and (VIIId) showing good anticancer activities against A549 cancer cell line.
ISSN:	0931-7597 1522-2667
DOI:	10.1002/chin.201503065