Green Synthesis of 3-Hydroxynaphthalene-1,4-dione Derivatives via Microwave-Assisted Three-Component Reactions in Neat Water

A novel and efficient access to 2‐(argio(3‐methyl‐5‐oxo‐1‐phenyl‐4,5‐dihydro‐1H‐pyrazol‐4‐yl)methyl)‐3‐hydroxynaphthalene‐1,4‐dione derivatives from readily available substrates in neat water is described with aid of microwave irradiation. The results of our study provide a green, simple and practic...

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Veröffentlicht in:Journal of heterocyclic chemistry 2012-05, Vol.49 (3), p.521-525
Hauptverfasser: Wang, Shu-Liang, Ding, Jie, Shi, Fen, Liu, Yin-Ping, Jiang, Bo, Ma, Ning, Tu, Shu-Jiang
Format: Artikel
Sprache:eng
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Zusammenfassung:A novel and efficient access to 2‐(argio(3‐methyl‐5‐oxo‐1‐phenyl‐4,5‐dihydro‐1H‐pyrazol‐4‐yl)methyl)‐3‐hydroxynaphthalene‐1,4‐dione derivatives from readily available substrates in neat water is described with aid of microwave irradiation. The results of our study provide a green, simple and practical one‐pot approach to the synthesis of 3‐hydroxynaphthalene‐1,4‐dione analogs in excellent yields without further purification.
ISSN:0022-152X
1943-5193
DOI:10.1002/jhet.798