Antigenic specificity of a monovalentversuspolyvalent MOMP basedChlamydia pecorumvaccine in koalas (Phascolarctos cinereus)

Highlights * Tested immunogenicity of monoversuspolyvalent MOMP basedChlamydia pecorumvaccine in koalas. * Immunisation produced plasma and mucosal antibodies to various MOMP antigens. * Upon vaccination animals neutralised various heterologousC. pecoruminfections. * Demonstrated strong cellular imm...

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Veröffentlicht in:	Vaccine 2013-02, Vol.31 (8), p.1217
Hauptverfasser:	Kollipara, Avinash, Wan, Charles, Rawlinson, Galit, Brumm, Jacqui, Nilsson, Karen, Polkinghorne, Adam, Beagley, Kenneth, Timms, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Immune system Immunization Immunogenicity Lymphocytes Sexually transmitted diseases STD Vaccines Women
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Highlights * Tested immunogenicity of monoversuspolyvalent MOMP basedChlamydia pecorumvaccine in koalas. * Immunisation produced plasma and mucosal antibodies to various MOMP antigens. * Upon vaccination animals neutralised various heterologousC. pecoruminfections. * Demonstrated strong cellular immune responses to various antigens andC. pecorumEBs. * Unveils the feasibility of developing an effective MOMP basedC. pecorumvaccine.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2012.12.057