Live oral typhoid vaccineSalmonellaTyphi Ty21a - A surrogate vaccine against non-typhoid salmonella?
Highlights * There are no vaccines available against non-typhoid Salmonella (NTS). * Intestinal antibodies against O-antigens have proven protective in animal studies. * Oral typhoid vaccine Ty21a effectively elicits intestinal antibodies to O-antigens. * These antibodies cross-react with common NTS...
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| Veröffentlicht in: | Vaccine 2012-11, Vol.30 (50), p.7238 |
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| container_title | Vaccine |
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| creator | Kantele, Anu Pakkanen, Sari H Siitonen, Anja Karttunen, Riitta Kantele, Jussi M |
| description | Highlights * There are no vaccines available against non-typhoid Salmonella (NTS). * Intestinal antibodies against O-antigens have proven protective in animal studies. * Oral typhoid vaccine Ty21a effectively elicits intestinal antibodies to O-antigens. * These antibodies cross-react with common NTS strains, such asSalmonellaEnteritidis. * Ty21a may have cross-protective efficacy against numerous NTS strains. |
| doi_str_mv | 10.1016/j.vaccine.2012.10.002 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 0264-410X |
| ispartof | Vaccine, 2012-11, Vol.30 (50), p.7238 |
| issn | 0264-410X 1873-2518 |
| language | eng |
| recordid | cdi_proquest_journals_1625879172 |
| source | ScienceDirect Journals (5 years ago - present); ProQuest Central UK/Ireland |
| subjects | Antimicrobial agents Bacteria Confidence intervals Females Fever Hospitals Salmonella Typhoid Vaccines |
| title | Live oral typhoid vaccineSalmonellaTyphi Ty21a - A surrogate vaccine against non-typhoid salmonella? |
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