Live oral typhoid vaccineSalmonellaTyphi Ty21a - A surrogate vaccine against non-typhoid salmonella?

Live oral typhoid vaccineSalmonellaTyphi Ty21a - A surrogate vaccine against non-typhoid salmonella?

Highlights * There are no vaccines available against non-typhoid Salmonella (NTS). * Intestinal antibodies against O-antigens have proven protective in animal studies. * Oral typhoid vaccine Ty21a effectively elicits intestinal antibodies to O-antigens. * These antibodies cross-react with common NTS...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Vaccine 2012-11, Vol.30 (50), p.7238
Hauptverfasser: Kantele, Anu, Pakkanen, Sari H, Siitonen, Anja, Karttunen, Riitta, Kantele, Jussi M
Format: Artikel
Sprache:eng
Schlagworte:
Antimicrobial agents
Bacteria
Confidence intervals
Females
Fever
Hospitals
Salmonella
Typhoid
Vaccines
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Highlights * There are no vaccines available against non-typhoid Salmonella (NTS). * Intestinal antibodies against O-antigens have proven protective in animal studies. * Oral typhoid vaccine Ty21a effectively elicits intestinal antibodies to O-antigens. * These antibodies cross-react with common NTS strains, such asSalmonellaEnteritidis. * Ty21a may have cross-protective efficacy against numerous NTS strains.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2012.10.002