Safety and vaccine efficacy of a glycoprotein G deficient strain of infectious laryngotracheitis virus deliveredin ovo

Safety and vaccine efficacy of a glycoprotein G deficient strain of infectious laryngotracheitis virus deliveredin ovo

Highlights * A candidate vaccine strain of ILTV, deficient in glycoprotein G, was givenin ovo. * Three vaccine doses were tested for safety and efficacy. * All doses proved to be safe, with no difference in weight gain up to 3 weeks of age. * The highest dose was the most efficacious after challenge...

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Veröffentlicht in:Vaccine 2012-11, Vol.30 (50), p.7193
Hauptverfasser: Legione, Alistair R, Coppo, Mauricio JC, Lee, Sang-Won, Noormohammadi, Amir H, Hartley, Carol A, Browning, Glenn F, Gilkerson, James R, O'Rourke, Denise, Devlin, Joanne M
Format: Artikel
Sprache:eng
Schlagworte:
Birds
Deoxyribonucleic acid
DNA
Drinking water
Eggs
Embryos
Histopathology
Methods
Vaccines
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Beschreibung
Zusammenfassung:Highlights * A candidate vaccine strain of ILTV, deficient in glycoprotein G, was givenin ovo. * Three vaccine doses were tested for safety and efficacy. * All doses proved to be safe, with no difference in weight gain up to 3 weeks of age. * The highest dose was the most efficacious after challenge.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2012.10.023