Outer membrane vesicles (OMV) production ofNeisseria meningitidisserogroup B in batch process

Outer membrane vesicles (OMV) production ofNeisseria meningitidisserogroup B in batch process

Highlights * Outer membrane vesicles production byNeisseria meningitidisunder four different conditions. * Glycerol in the culture medium was not consumed during cultivation. * The results suggest that lactate is a main limiting growth factor. * Maximum amount of outer membrane vesicles with iron re...

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Veröffentlicht in:Vaccine 2012-09, Vol.30 (42), p.6064
Hauptverfasser: Santos, Sílvia, Arauz, Luciana Juncioni de, Baruque-Ramos, Júlia, Lebrun, Ivo, Carneiro, Sylvia Mendes, Barreto, Sandra Alves, Schenkman, Rocilda Perazzini Furtado
Format: Artikel
Sprache:eng
Schlagworte:
Amino acids
Antigens
Bacteriology
Behavior
Biomass
Carbon
Experiments
Glycerol
Proteins
Studies
Vaccines
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Beschreibung
Zusammenfassung:Highlights * Outer membrane vesicles production byNeisseria meningitidisunder four different conditions. * Glycerol in the culture medium was not consumed during cultivation. * The results suggest that lactate is a main limiting growth factor. * Maximum amount of outer membrane vesicles with iron regulated proteins was obtained during stationary growth.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2012.07.052