CXCR2 inhibition protects against chronic pancreatitis in a murine model
To examine the importance of neutrophils in this process we used a neutrophil blocking antibody and found that there was significant pancreatic damage from macrophage infiltration despite neutrophil blockade. [...]CXCR2 inhibition may protect patients with early chronic pancreatitis from pancreatic...
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| Veröffentlicht in: | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2013-01, Vol.13 (1), p.e5-e5 |
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| container_title | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] |
| container_volume | 13 |
| creator | Steele, C.W Morton, J.P McKay, C.J Evans, T.R.J Carter, C.R Sansom, O.J |
| description | To examine the importance of neutrophils in this process we used a neutrophil blocking antibody and found that there was significant pancreatic damage from macrophage infiltration despite neutrophil blockade. [...]CXCR2 inhibition may protect patients with early chronic pancreatitis from pancreatic damage in a process dependent on both neutrophil and macrophage chemotaxis. |
| doi_str_mv | 10.1016/j.pan.2012.12.016 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1424-3903 |
| ispartof | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.], 2013-01, Vol.13 (1), p.e5-e5 |
| issn | 1424-3903 1424-3911 |
| language | eng |
| recordid | cdi_proquest_journals_1620595953 |
| source | Alma/SFX Local Collection |
| subjects | Chemokines Endocrinology & Metabolism Gastroenterology and Hepatology Pancreas Rodents |
| title | CXCR2 inhibition protects against chronic pancreatitis in a murine model |
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