Myxomavirusas a vector for the immunisation of sheep: Protection study against challenge with bluetongue virus

Myxomavirusas a vector for the immunisation of sheep: Protection study against challenge with bluetongue virus

Highlights *Myxomavirus(MYXV) is efficient at priming antibody responses in ruminants. * MYXV potential for vaccination in sheep was confirmed against bluetongue challenge. * High expression of antigen by MYXV is critical for efficient immunisation in sheep.

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Bibliographische Detailangaben
Veröffentlicht in:Vaccine 2012-02, Vol.30 (9), p.1609
Hauptverfasser: Top, Sokunthea, Foucras, Gilles, Deplanche, Martine, Rives, Germain, Calvalido, Jérôme, Comtet, Loic, Bertagnoli, Stéphane, Meyer, Gilles
Format: Artikel
Sprache:eng
Schlagworte:
Experiments
Gene expression
Immunization
Plasmids
Protein expression
Proteins
Studies
Vaccines
Viruses
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Beschreibung
Zusammenfassung:Highlights *Myxomavirus(MYXV) is efficient at priming antibody responses in ruminants. * MYXV potential for vaccination in sheep was confirmed against bluetongue challenge. * High expression of antigen by MYXV is critical for efficient immunisation in sheep.
ISSN:0264-410X
1873-2518
DOI:10.1016/j.vaccine.2011.12.108