The immune enhancement of a novel soy lecithin/[beta]-glucans based adjuvant on nativeNeospora caninumtachyzoite extract vaccine in mice

The immune enhancement of a novel soy lecithin/[beta]-glucans based adjuvant on nativeNeospora caninumtachyzoite extract vaccine in mice

Highlights * We demonstrate the immune enhancement of a tailoredN. caninumvaccine in mice. * Vaccine antigen was selected based on its capacity to activate dendritic cells. * Vaccines withProvidean-AVEC®adjuvant limitedN. caninuminfection. * A tenth of the antigen payload was needed compared to othe...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Vaccine 2012-02, Vol.30 (6), p.1124
Hauptverfasser: Mansilla, Florencia Celeste, Franco-Mahecha, Olga Lucía, Lavoria, María Ángeles, Moore, Dadín Prando, Giraldez, Adrián Nicolás, Iglesias, Marcela Elvira, Wilda, Maximiliano, Capozzo, Alejandra Victoria
Format: Artikel
Sprache:eng
Schlagworte:
Medical research
Parasites
Studies
Vaccines
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue 6
container_start_page 1124
container_title Vaccine
container_volume 30
creator Mansilla, Florencia Celeste
Franco-Mahecha, Olga Lucía
Lavoria, María Ángeles
Moore, Dadín Prando
Giraldez, Adrián Nicolás
Iglesias, Marcela Elvira
Wilda, Maximiliano
Capozzo, Alejandra Victoria
description Highlights * We demonstrate the immune enhancement of a tailoredN. caninumvaccine in mice. * Vaccine antigen was selected based on its capacity to activate dendritic cells. * Vaccines withProvidean-AVEC®adjuvant limitedN. caninuminfection. * A tenth of the antigen payload was needed compared to other aqueous adjuvants. * Protective responses againstN. caninumentailed systemic IgG2a and IFN-γ.
doi_str_mv 10.1016/j.vaccine.2011.12.007
format Article
fullrecord <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_journals_1618948521</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3477149141</sourcerecordid><originalsourceid>FETCH-proquest_journals_16189485213</originalsourceid><addsrcrecordid>eNqNjs1Kw0AUhQdRMP48gnDBddK5-Wu6FsWVqy4EkXI7vTUTkjs1MxOsT-BjG6EP4OoszvdxjlJ3qDPUWC-6bCJjrHCWa8QM80zr5ZlKsFkWaV5hc64SnddlWqJ-vVRX3nda66rAVaJ-1i2DHYYoDCwtieGBJYDbA4G4iXvw7gg9GxtaK4u3LQd6Tz_6aEg8bMnzDmjXxYn-LAGhYCd-YecPbiSYKStxCGTa47ezYV75CiOZAKfPYAUGa_hGXeyp93x7ymt1__S4fnhOD6P7jOzDpnNxlLnaYI3NqmyqHIv_Ub_7a110</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1618948521</pqid></control><display><type>article</type><title>The immune enhancement of a novel soy lecithin/[beta]-glucans based adjuvant on nativeNeospora caninumtachyzoite extract vaccine in mice</title><source>Elsevier ScienceDirect Journals Complete</source><source>ProQuest Central UK/Ireland</source><creator>Mansilla, Florencia Celeste ; Franco-Mahecha, Olga Lucía ; Lavoria, María Ángeles ; Moore, Dadín Prando ; Giraldez, Adrián Nicolás ; Iglesias, Marcela Elvira ; Wilda, Maximiliano ; Capozzo, Alejandra Victoria</creator><creatorcontrib>Mansilla, Florencia Celeste ; Franco-Mahecha, Olga Lucía ; Lavoria, María Ángeles ; Moore, Dadín Prando ; Giraldez, Adrián Nicolás ; Iglesias, Marcela Elvira ; Wilda, Maximiliano ; Capozzo, Alejandra Victoria</creatorcontrib><description>Highlights * We demonstrate the immune enhancement of a tailoredN. caninumvaccine in mice. * Vaccine antigen was selected based on its capacity to activate dendritic cells. * Vaccines withProvidean-AVEC®adjuvant limitedN. caninuminfection. * A tenth of the antigen payload was needed compared to other aqueous adjuvants. * Protective responses againstN. caninumentailed systemic IgG2a and IFN-γ.</description><identifier>ISSN: 0264-410X</identifier><identifier>EISSN: 1873-2518</identifier><identifier>DOI: 10.1016/j.vaccine.2011.12.007</identifier><language>eng</language><publisher>Kidlington: Elsevier Limited</publisher><subject>Medical research ; Parasites ; Studies ; Vaccines</subject><ispartof>Vaccine, 2012-02, Vol.30 (6), p.1124</ispartof><rights>Copyright Elsevier Limited Feb 1, 2012</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1618948521?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,27924,27925,64385,64389,72469</link.rule.ids></links><search><creatorcontrib>Mansilla, Florencia Celeste</creatorcontrib><creatorcontrib>Franco-Mahecha, Olga Lucía</creatorcontrib><creatorcontrib>Lavoria, María Ángeles</creatorcontrib><creatorcontrib>Moore, Dadín Prando</creatorcontrib><creatorcontrib>Giraldez, Adrián Nicolás</creatorcontrib><creatorcontrib>Iglesias, Marcela Elvira</creatorcontrib><creatorcontrib>Wilda, Maximiliano</creatorcontrib><creatorcontrib>Capozzo, Alejandra Victoria</creatorcontrib><title>The immune enhancement of a novel soy lecithin/[beta]-glucans based adjuvant on nativeNeospora caninumtachyzoite extract vaccine in mice</title><title>Vaccine</title><description>Highlights * We demonstrate the immune enhancement of a tailoredN. caninumvaccine in mice. * Vaccine antigen was selected based on its capacity to activate dendritic cells. * Vaccines withProvidean-AVEC®adjuvant limitedN. caninuminfection. * A tenth of the antigen payload was needed compared to other aqueous adjuvants. * Protective responses againstN. caninumentailed systemic IgG2a and IFN-γ.</description><subject>Medical research</subject><subject>Parasites</subject><subject>Studies</subject><subject>Vaccines</subject><issn>0264-410X</issn><issn>1873-2518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2012</creationdate><recordtype>article</recordtype><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqNjs1Kw0AUhQdRMP48gnDBddK5-Wu6FsWVqy4EkXI7vTUTkjs1MxOsT-BjG6EP4OoszvdxjlJ3qDPUWC-6bCJjrHCWa8QM80zr5ZlKsFkWaV5hc64SnddlWqJ-vVRX3nda66rAVaJ-1i2DHYYoDCwtieGBJYDbA4G4iXvw7gg9GxtaK4u3LQd6Tz_6aEg8bMnzDmjXxYn-LAGhYCd-YecPbiSYKStxCGTa47ezYV75CiOZAKfPYAUGa_hGXeyp93x7ymt1__S4fnhOD6P7jOzDpnNxlLnaYI3NqmyqHIv_Ub_7a110</recordid><startdate>20120201</startdate><enddate>20120201</enddate><creator>Mansilla, Florencia Celeste</creator><creator>Franco-Mahecha, Olga Lucía</creator><creator>Lavoria, María Ángeles</creator><creator>Moore, Dadín Prando</creator><creator>Giraldez, Adrián Nicolás</creator><creator>Iglesias, Marcela Elvira</creator><creator>Wilda, Maximiliano</creator><creator>Capozzo, Alejandra Victoria</creator><general>Elsevier Limited</general><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7T2</scope><scope>7T5</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope></search><sort><creationdate>20120201</creationdate><title>The immune enhancement of a novel soy lecithin/[beta]-glucans based adjuvant on nativeNeospora caninumtachyzoite extract vaccine in mice</title><author>Mansilla, Florencia Celeste ; Franco-Mahecha, Olga Lucía ; Lavoria, María Ángeles ; Moore, Dadín Prando ; Giraldez, Adrián Nicolás ; Iglesias, Marcela Elvira ; Wilda, Maximiliano ; Capozzo, Alejandra Victoria</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_journals_16189485213</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2012</creationdate><topic>Medical research</topic><topic>Parasites</topic><topic>Studies</topic><topic>Vaccines</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mansilla, Florencia Celeste</creatorcontrib><creatorcontrib>Franco-Mahecha, Olga Lucía</creatorcontrib><creatorcontrib>Lavoria, María Ángeles</creatorcontrib><creatorcontrib>Moore, Dadín Prando</creatorcontrib><creatorcontrib>Giraldez, Adrián Nicolás</creatorcontrib><creatorcontrib>Iglesias, Marcela Elvira</creatorcontrib><creatorcontrib>Wilda, Maximiliano</creatorcontrib><creatorcontrib>Capozzo, Alejandra Victoria</creatorcontrib><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><jtitle>Vaccine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mansilla, Florencia Celeste</au><au>Franco-Mahecha, Olga Lucía</au><au>Lavoria, María Ángeles</au><au>Moore, Dadín Prando</au><au>Giraldez, Adrián Nicolás</au><au>Iglesias, Marcela Elvira</au><au>Wilda, Maximiliano</au><au>Capozzo, Alejandra Victoria</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The immune enhancement of a novel soy lecithin/[beta]-glucans based adjuvant on nativeNeospora caninumtachyzoite extract vaccine in mice</atitle><jtitle>Vaccine</jtitle><date>2012-02-01</date><risdate>2012</risdate><volume>30</volume><issue>6</issue><spage>1124</spage><pages>1124-</pages><issn>0264-410X</issn><eissn>1873-2518</eissn><abstract>Highlights * We demonstrate the immune enhancement of a tailoredN. caninumvaccine in mice. * Vaccine antigen was selected based on its capacity to activate dendritic cells. * Vaccines withProvidean-AVEC®adjuvant limitedN. caninuminfection. * A tenth of the antigen payload was needed compared to other aqueous adjuvants. * Protective responses againstN. caninumentailed systemic IgG2a and IFN-γ.</abstract><cop>Kidlington</cop><pub>Elsevier Limited</pub><doi>10.1016/j.vaccine.2011.12.007</doi></addata></record>
fulltext fulltext
identifier ISSN: 0264-410X
ispartof Vaccine, 2012-02, Vol.30 (6), p.1124
issn 0264-410X
1873-2518
language eng
recordid cdi_proquest_journals_1618948521
source Elsevier ScienceDirect Journals Complete; ProQuest Central UK/Ireland
subjects Medical research
Parasites
Studies
Vaccines
title The immune enhancement of a novel soy lecithin/[beta]-glucans based adjuvant on nativeNeospora caninumtachyzoite extract vaccine in mice
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-29T07%3A40%3A09IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=The%20immune%20enhancement%20of%20a%20novel%20soy%20lecithin/%5Bbeta%5D-glucans%20based%20adjuvant%20on%20nativeNeospora%20caninumtachyzoite%20extract%20vaccine%20in%20mice&rft.jtitle=Vaccine&rft.au=Mansilla,%20Florencia%20Celeste&rft.date=2012-02-01&rft.volume=30&rft.issue=6&rft.spage=1124&rft.pages=1124-&rft.issn=0264-410X&rft.eissn=1873-2518&rft_id=info:doi/10.1016/j.vaccine.2011.12.007&rft_dat=%3Cproquest%3E3477149141%3C/proquest%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1618948521&rft_id=info:pmid/&rfr_iscdi=true