Pioglitazone attenuates alcohol-induced alveolar macrophage oxidative stress and dysfunction by up-regulating microRNA-92a/b

Pioglitazone attenuates alcohol-induced alveolar macrophage oxidative stress and dysfunction by up-regulating microRNA-92a/b

Alcohol abuse increases risk of respiratory infections through impaired lung immunity mediated by enhanced oxidative stress and alveolar macrophage (AM) phagocytic dysfunction.

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Bibliographische Detailangaben
Veröffentlicht in:Alcohol (Fayetteville, N.Y.) N.Y.), 2014-11, Vol.48 (7), p.734-734
Hauptverfasser: Yeligar, S.M, Harris, F.L, Brown, L.A.S, Hart, C.M
Format: Artikel
Sprache:eng
Schlagworte:
Alcohol
Ethanol
MicroRNAs
Oxidative stress
Psychiatry
Rodents
Online-Zugang:Volltext
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Beschreibung
Zusammenfassung:Alcohol abuse increases risk of respiratory infections through impaired lung immunity mediated by enhanced oxidative stress and alveolar macrophage (AM) phagocytic dysfunction.
ISSN:0741-8329
1873-6823
DOI:10.1016/j.alcohol.2014.09.030