Antiretroviral therapy attenuates dysregulated hematopoiesis caused by chronic binge alcohol and SIV infection in rhesus macaques

Antiretroviral therapy attenuates dysregulated hematopoiesis caused by chronic binge alcohol and SIV infection in rhesus macaques

Following the 10 weeks ART administration period, we observed decreased frequencies of long-term hematopoietic stem cells and multipotent progenitor cells in CBA, ART naïve animals, and this deficit was not observed in ART-treated animals.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Alcohol (Fayetteville, N.Y.) N.Y.), 2014-11, Vol.48 (7), p.730-730
Hauptverfasser: Li, L.W, Bagby, G.J, Nelson, S, Molina, P.E, Welsh, D.A, Siggins, R.W
Format: Artikel
Sprache:eng
Schlagworte:
Alcohol
Animals
Bone marrow
HIV
Human immunodeficiency virus
Infections
Psychiatry
Stem cells
Sucrose
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Following the 10 weeks ART administration period, we observed decreased frequencies of long-term hematopoietic stem cells and multipotent progenitor cells in CBA, ART naïve animals, and this deficit was not observed in ART-treated animals.
ISSN:0741-8329
1873-6823
DOI:10.1016/j.alcohol.2014.09.014