ChemInform Abstract: Directed Ruthenium-Catalyzed C(sp3)--H [alpha]-Alkylation of Cyclic Amines Using Dioxolane-Protected Alkenones

ChemInform Abstract: Directed Ruthenium-Catalyzed C(sp3)--H [alpha]-Alkylation of Cyclic Amines Using Dioxolane-Protected Alkenones

The pyridin-2-yl group is found to be an efficient directing group for the ruthenium catalyzed [alpha]-alkylation of cyclic amines using dioxolane protected alkenones (II) and (XVII) or ester (XX). [PUBLICATION ABSTRACT]

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Bibliographische Detailangaben
Veröffentlicht in:ChemInform 2014-09, Vol.45 (40)
Hauptverfasser: Kulago, Artem A, Van Steijvoort, Ben F, Mitchell, Emily A, Meerpoel, Lieven, Maes, Bert U W
Format: Artikel
Sprache:eng
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Zusammenfassung:The pyridin-2-yl group is found to be an efficient directing group for the ruthenium catalyzed [alpha]-alkylation of cyclic amines using dioxolane protected alkenones (II) and (XVII) or ester (XX). [PUBLICATION ABSTRACT]
ISSN:0931-7597
1522-2667
DOI:10.1002/chin.201440164