Enhancement of T cell-mediated immune responses to whole inactivated influenza virus by chloroquine treatmentin vivo

Highlights * Chloroquine improves cross-presentation of nonreplicating influenza virusin vitro.* Immunization combined with chloroquine improves primary and memory T cells. * Chloroquine reduces viral load following pulmonary challenge of mice with PR8 virus.

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Veröffentlicht in:Vaccine 2013-03, Vol.31 (13), p.1717
Hauptverfasser: Garulli, Bruno, Di Mario, Giuseppina, Sciaraffia, Ester, Accapezzato, Daniele, Barnaba, Vincenzo, Castrucci, Maria R
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container_end_page
container_issue 13
container_start_page 1717
container_title Vaccine
container_volume 31
creator Garulli, Bruno
Di Mario, Giuseppina
Sciaraffia, Ester
Accapezzato, Daniele
Barnaba, Vincenzo
Castrucci, Maria R
description Highlights * Chloroquine improves cross-presentation of nonreplicating influenza virusin vitro.* Immunization combined with chloroquine improves primary and memory T cells. * Chloroquine reduces viral load following pulmonary challenge of mice with PR8 virus.
doi_str_mv 10.1016/j.vaccine.2013.01.037
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source ScienceDirect Journals (5 years ago - present); ProQuest Central UK/Ireland
subjects Antigens
Cytokines
Drug dosages
Experiments
Immune system
Immunization
Infections
Influenza
Lymphocytes
Peptides
Spleen
Studies
T cell receptors
Vaccines
Viral infections
title Enhancement of T cell-mediated immune responses to whole inactivated influenza virus by chloroquine treatmentin vivo
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