CD21-/lowB Cells Are Increased in Both Common Variable Immune Deficiency (CVID) and Specific Antibody Deficiency(SAD)

CD21-/lowB Cells Are Increased in Both Common Variable Immune Deficiency (CVID) and Specific Antibody Deficiency(SAD)

Using fresh whole blood samples multiple parameter flow cytometry analysis enumerated CD19/CD27 with extended markers including surface IgM/IgD and CD21 in 37 healthy controls (HC), 31 CVID subjects, and 8 SAD defined as subjects with recurrent infections and decreased antibody response to polysacch...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of allergy and clinical immunology 2011-02, Vol.127 (2), p.AB135
Hauptverfasser: Elizalde, A, Hudey, S, Dorsey, M, Perez, E, Sleasman, J, Sriaroon, P
Format: Artikel
Sprache:eng
Schlagworte:
Antigens
Immune system
Immunoglobulins
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Using fresh whole blood samples multiple parameter flow cytometry analysis enumerated CD19/CD27 with extended markers including surface IgM/IgD and CD21 in 37 healthy controls (HC), 31 CVID subjects, and 8 SAD defined as subjects with recurrent infections and decreased antibody response to polysaccharide vaccine.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2010.12.539