Risk of Potentially Life-Threatening Thyroid Dysfunction Due to Amiodarone in Idiopathic Pulmonary Arterial Hypertension Patients

[...]we decided to study amiodarone use and thyroid function in pulmonary hypertension. [...]we noted that the prevalence of AITD in CTEPH was 17%, which is in keeping with the prevalence of AITD in left heart disease. [...]we infer that the presence of pulmonary hypertension per se does not increas...

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Veröffentlicht in:	Journal of the American College of Cardiology 2011-02, Vol.57 (8), p.997-998
Hauptverfasser:	Soon, Elaine, MBBChir, Toshner, Mark, MBBS, Mela, Marianna, MBBS, Grace, Andrew, PhD, Sheares, Karen, PhD, Morrell, Nicholas, MD, Pepke-Zaba, Joanna, PhD
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged amiodarone Amiodarone - adverse effects Amiodarone - therapeutic use Cardiology Cardiovascular Cardiovascular disease Case-Control Studies Dose-Response Relationship, Drug Drug therapy Female Humans Hypertension, Pulmonary - diagnosis Hypertension, Pulmonary - drug therapy Hyperthyroidism - chemically induced Hyperthyroidism - mortality Hyperthyroidism - physiopathology Internal Medicine Male Middle Aged Multivariate analysis Prognosis Pulmonary arteries Pulmonary hypertension Reference Values Retrospective Studies Risk Assessment Severity of Illness Index Survival Rate thyroid Thyroid diseases Thyroid Function Tests Treatment Outcome Vasodilator Agents - adverse effects Vasodilator Agents - therapeutic use
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Beschreibung
Zusammenfassung:	[...]we decided to study amiodarone use and thyroid function in pulmonary hypertension. [...]we noted that the prevalence of AITD in CTEPH was 17%, which is in keeping with the prevalence of AITD in left heart disease. [...]we infer that the presence of pulmonary hypertension per se does not increase the risk of AITD, but rather the presence of idiopathic pulmonary hypertension.
ISSN:	0735-1097 1558-3597
DOI:	10.1016/j.jacc.2010.09.059