Efectos conductuales del consumo espontáneo de alcohol en ratones NRMI bajo estrés discontinuo/Spontaneous alcohol consumption behavior effects on NMRI mice under discontinuous stress
With the aim to evaluate the effects of spontaneous alcohol consumption on NMRI mice submitted to discontinuous stress. We designed a 4 experimental groups: Control (n=21), control-stress (n=25), Alcohol (n=23) and Alcohol-stress (n=31); witch posterior to pre-trials, received ethanol (10%) and wate...
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Veröffentlicht in: | Archivos venezolanos de farmacología y terapéutica 2013-04, Vol.32 (2), p.39 |
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Sprache: | spa |
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Zusammenfassung: | With the aim to evaluate the effects of spontaneous alcohol consumption on NMRI mice submitted to discontinuous stress. We designed a 4 experimental groups: Control (n=21), control-stress (n=25), Alcohol (n=23) and Alcohol-stress (n=31); witch posterior to pre-trials, received ethanol (10%) and water ad libitum and were subject of force swimming test at 5°C for 1minnute three times/week. Succeeding, we evaluate locomotor activity in motility cage, anxiety on cross maze and working memory on 8-arm radial maze. All pre-trials results were same; likewise a significant higher percent of alcohol-stress group remaining more time in open arms than closed at cross maze, vertical hypomotility and displayed expend more time to solve the radial maze, all compared against the others groups. The results that stress behavior potentiate behavior disturbance observed in alcoholic animals. |
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ISSN: | 0798-0264 2610-7988 |