NO ASSOCIATION OF PARAOXONASE-1 Q192R AND THROMBOTIC EVENTS DURING DUAL ANTI-PLATELET THERAPY IN PATIENTS AFTER ACUTE MYOCARDIAL INFARCTION

NO ASSOCIATION OF PARAOXONASE-1 Q192R AND THROMBOTIC EVENTS DURING DUAL ANTI-PLATELET THERAPY IN PATIENTS AFTER ACUTE MYOCARDIAL INFARCTION

Conclusion PON1 Q192R genotype was not associated with recurrent thrombotic events in patients with AMI infarction undergoing primary PCI and treated with dual antiplatelet therapy, whereas CYP2C19*2*2 carriers did have an increased risk of antiplatelet treatment failure.

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Veröffentlicht in:Journal of the American College of Cardiology 2012-03, Vol.59 (13), p.E458-E458
Hauptverfasser: Verschuren, Jeffrey JW, Boden, Hel&egrave, n, Wessels, Judith A, van der Hoeven, B.L, Guchelaar, Henk-Jan, Schalij, Martin, Jukema, Johan
Format: Artikel
Sprache:eng
Schlagworte:
Cardiology
Cardiovascular
Drug therapy
Genotype & phenotype
Heart attacks
Internal Medicine
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Zusammenfassung:Conclusion PON1 Q192R genotype was not associated with recurrent thrombotic events in patients with AMI infarction undergoing primary PCI and treated with dual antiplatelet therapy, whereas CYP2C19*2*2 carriers did have an increased risk of antiplatelet treatment failure.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(12)60459-8