BAYESIAN META-ANALYSIS AND NET CLINICAL BENEFIT OF CLOPIDOGREL AND PROTON PUMP INHIBITORS IN ADVERSE CARDIOVASCULAR AND GASTROINTESTINAL EVENTS

BAYESIAN META-ANALYSIS AND NET CLINICAL BENEFIT OF CLOPIDOGREL AND PROTON PUMP INHIBITORS IN ADVERSE CARDIOVASCULAR AND GASTROINTESTINAL EVENTS

Conclusions Despite recent studies prompting an FDA warning regarding an interaction between clopidogrel and proton-pump inhibitors, Bayesian meta-analysis suggests little to no clinical impact of this interaction on major adverse cardiovascular events.

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Veröffentlicht in:Journal of the American College of Cardiology 2012-03, Vol.59 (13), p.E1763-E1763
Hauptverfasser: Lang, Christopher, Gullickson, Donald, Bartosz, Caren, Mathew, Roshin, Arora, Rohit
Format: Artikel
Sprache:eng
Schlagworte:
Cardiology
Cardiovascular
Drug therapy
Heart attacks
Internal Medicine
Meta-analysis
Probability
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Zusammenfassung:Conclusions Despite recent studies prompting an FDA warning regarding an interaction between clopidogrel and proton-pump inhibitors, Bayesian meta-analysis suggests little to no clinical impact of this interaction on major adverse cardiovascular events.
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(12)61764-1