CILOSTAZOL, A PHOSPHODIESTERASE III INHIBITOR, INCREASES CAMP LEVELS AND AUGMENTS THE INFARCT SIZE LIMITING EFFECT OF A DPP4 INHIBITOR IN MICE WITH TYPE-2 DIABETES MELLITUS

CILOSTAZOL, A PHOSPHODIESTERASE III INHIBITOR, INCREASES CAMP LEVELS AND AUGMENTS THE INFARCT SIZE LIMITING EFFECT OF A DPP4 INHIBITOR IN MICE WITH TYPE-2 DIABETES MELLITUS

Activation of the GLP-1 receptors increases intracellular cAMP with downstream activation of protein kinase A (PKA).

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Veröffentlicht in:Journal of the American College of Cardiology 2012-03, Vol.59 (13), p.E540-E540
Hauptverfasser: Birnbaum, Yochai, Ling, Shukuan, Castillo, Alexander, Perez-Polo, Jose R, Ye, Yumei
Format: Artikel
Sprache:eng
Schlagworte:
Cardiology
Cardiovascular
Diabetes
Internal Medicine
Kinases
Rodents
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Zusammenfassung:Activation of the GLP-1 receptors increases intracellular cAMP with downstream activation of protein kinase A (PKA).
ISSN:0735-1097
1558-3597
DOI:10.1016/S0735-1097(12)60541-5