Hepatitis A vaccine failure: how to treat the threat

[...]a seroconversion rate of 98.1% has been observed in one "in the field" vaccination trial (Mele, unpublished observations). [...]a small proportion of non-responders may exist. [4] indicate that vaccination may not be synonymous to protection. Since travellers to endemic countries are exposed to the most significant risk of HAV infection and they often seek medical advice before leaving, correct counselling consisting in the recommendation of continuous adherence to the universal safety measures for the prevention of faecal-oral infections should be strongly advised.