ChemInform Abstract: Bio-Inspired Formal Synthesis of Hirsutellones A-C Featuring an Electrophilic Cyclization Triggered by Remote Lewis Acid-Activation

A bio‐inspired strategy is used to complete the formal synthesis of the antitubercular hirsutellone B (I) and congeners A (II) and C (III), through construction of its decahydrofluorene core from a linear polyene strand activated at both ends by a silyl enol ether and an allyl acetate (not shown).

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Bibliographische Detailangaben
Veröffentlicht in:	ChemInform 2014-05, Vol.45 (19), p.no-no
Hauptverfasser:	Li, Xu-Wen, Ear, Alexandre, Roger, Lukas, Riache, Nassima, Deville, Alexandre, Nay, Bastien
Format:	Artikel
Sprache:	eng
Schlagworte:	other bioactive products ring closure reactions
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	A bio‐inspired strategy is used to complete the formal synthesis of the antitubercular hirsutellone B (I) and congeners A (II) and C (III), through construction of its decahydrofluorene core from a linear polyene strand activated at both ends by a silyl enol ether and an allyl acetate (not shown).
ISSN:	0931-7597 1522-2667
DOI:	10.1002/chin.201419225