Cover Picture: The Catalytic Asymmetric Knoevenagel Condensation (Angew. Chem. Int. Ed. 7/2011)

The annual rings of the pictured tree represent the time gap, 116 years, between the discovery of the Knoevenagel condensation and that of the first catalytic asymmetric variant. As described by B. List et al. in their Communication on page 1707 ff., a cinchona amine catalyst promotes the reaction o...

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Veröffentlicht in:Angewandte Chemie International Edition 2011-02, Vol.50 (7), p.1447-1447
Hauptverfasser: Lee, Anna, Michrowska, Anna, Sulzer-Mosse, Sarah, List, Benjamin
Format: Artikel
Sprache:eng
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Zusammenfassung:The annual rings of the pictured tree represent the time gap, 116 years, between the discovery of the Knoevenagel condensation and that of the first catalytic asymmetric variant. As described by B. List et al. in their Communication on page 1707 ff., a cinchona amine catalyst promotes the reaction of α‐branched aldehydes and malonates through a dynamic kinetic resolution to give alkylidene malonates with high enantioselectivity.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201000522