pH-Tunable Calcium Phosphate Covered Mesoporous Silica Nanocontainers for Intracellular Controlled Release of Guest Drugs

Springing the trap: A pH‐responsive mesoporous silica nanoparticle with a calcium phosphate (CaP) pore‐blocking coating was developed by enzyme‐mediated surface mineralization under mild conditions. Upon exposure to cellular lysosomal pH, guest anticancer drug was released from the pore by dissoluti...

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Veröffentlicht in:	Angewandte Chemie International Edition 2011-09, Vol.50 (38), p.8853-8857
Hauptverfasser:	Rim, Hwa Pyeong, Min, Kyung Hyun, Lee, Hong Jae, Jeong, Seo Young, Lee, Sang Cheon
Format:	Artikel
Sprache:	eng
Schlagworte:	drug delivery host-guest systems mesoporous materials mineralization nanoparticles
Online-Zugang:	Volltext
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