Relation between caffeine and behavioral symptoms in elderly patients with dementia: An observational study

OBJECTIVES: Caffeine is known to improve concentration and reduce fatigue in healthy adults, but high doses may induce anxiety and agitation. Because the effects of caffeine in elderly people with dementia are unknown, this study explores the relation between caffeine and behavioral symptoms in a gr...

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Veröffentlicht in:	The Journal of nutrition, health & aging health & aging, 2014-04, Vol.18 (4), p.407-410
Hauptverfasser:	Kromhout, Michelle A, Jongerling, J, Achterberg, W. P
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged, 80 and over Aging agitation Anxiety Apathy - drug effects Behavioral Symptoms - psychology Biological and medical sciences caffeine Caffeine - administration & dosage Caffeine - pharmacology correlation Dementia Dementia - complications Dementia - psychology elderly Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology Geriatrics/Gerontology Humans Male Medicine Medicine & Public Health Motor Skills - drug effects Netherlands Neurosciences Nursing Homes Nutrition observational studies patients people Pilot Projects Primary Care Medicine Quality of Life Research questionnaires sleep Sleep - drug effects Sleep Initiation and Maintenance Disorders - chemically induced Sleep Initiation and Maintenance Disorders - complications Surveys and Questionnaires Vertebrates: anatomy and physiology, studies on body, several organs or systems
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Zusammenfassung:	OBJECTIVES: Caffeine is known to improve concentration and reduce fatigue in healthy adults, but high doses may induce anxiety and agitation. Because the effects of caffeine in elderly people with dementia are unknown, this study explores the relation between caffeine and behavioral symptoms in a group of elderly patients with dementia. DESIGN: An observational pilot study. SETTING: A dementia special care unit of a Dutch nursing home. PARTICIPANTS: A total of 29 elderly patients with dementia. MEASUREMENTS: Behavioral symptoms were measured with the NPI-NH, and sleep and caffeine consumption were measured using questionnaires. RESULTS: A significant relation was found between the total amount of caffeine consumed during the day and apathy [Kendall’s tau (KT) −0.287 p=0.03], and the number of times that participants got up at night (KT 0.462; p
ISSN:	1279-7707 1760-4788
DOI:	10.1007/s12603-013-0417-9