mTOR expression in colorectal adenoma

mTOR expression in colorectal adenoma

[...]the results of our study suggest that mTOR is widely expressed in colorectal adenomas in a membranous pattern and cytoplasmic extravacuolar as well, warranting further evaluation of responsiveness to rapamycin or analogous treatment.

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Bibliographische Detailangaben
Veröffentlicht in:Human pathology 2014-04, Vol.45 (4), p.895-897
1. Verfasser: Handra-Luca, Adriana, MD, PhD
Format: Artikel
Sprache:eng
Schlagworte:
Adenocarcinoma - secondary
Adenoma - pathology
Classification
Colorectal cancer
Colorectal Neoplasms - pathology
Female
Gene Expression Regulation, Neoplastic
Humans
Male
Pathology
TOR Serine-Threonine Kinases - genetics
Tumors
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Beschreibung
Zusammenfassung:[...]the results of our study suggest that mTOR is widely expressed in colorectal adenomas in a membranous pattern and cytoplasmic extravacuolar as well, warranting further evaluation of responsiveness to rapamycin or analogous treatment.
ISSN:0046-8177
1532-8392
DOI:10.1016/j.humpath.2013.11.019