[18F]LBT-999, a new radioligand to study the dopamine transporter with PET: Characterization in baboons

[18F]LBT-999, a new radioligand to study the dopamine transporter with PET: Characterization in baboons

In PET study, the time course of the concentration of [18F]LBT-999 in different regions of the brain showed that the highest accumulation of [18F]LBT-999 was observed in the striatum with a peak uptake at 50 min (maximum = 5.7 ± 1.7 and 4.7 ± 1.0% ID/100 ml in putamen and caudate nucleus respectivel...

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Veröffentlicht in:NeuroImage (Orlando, Fla.) Fla.), 2006, Vol.31, p.T132-T132
Hauptverfasser: Saba, Wadad, Schöllhorn, M.-A., Valette, H., Chalon, S., Dolle, F., Garreau, L., Emond, P., Deloye, J.B., Guilloteau, D., Bottlaender, M.
Format: Artikel
Sprache:eng
Schlagworte:
Brain
Dopamine
Studies
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Zusammenfassung:In PET study, the time course of the concentration of [18F]LBT-999 in different regions of the brain showed that the highest accumulation of [18F]LBT-999 was observed in the striatum with a peak uptake at 50 min (maximum = 5.7 ± 1.7 and 4.7 ± 1.0% ID/100 ml in putamen and caudate nucleus respectively, n = 5).
ISSN:1053-8119
1095-9572
DOI:10.1016/j.neuroimage.2006.04.116