Cerebral nicotinic acetylcholine receptors in patients with Alzheimer's disease assessed with 2-[18F]F-A85380 PET—correlations to dementia severity

Cerebral nicotinic acetylcholine receptors in patients with Alzheimer's disease assessed with 2-[18F]F-A85380 PET—correlations to dementia severity

Objectives: For more than 20 years, post-mortem studies of the brains of those with Alzheimer's disease (AD) have consistently found damage or abnormalities in the nicotinic pathways projecting from the basal forebrain to cortical areas.

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Veröffentlicht in:NeuroImage (Orlando, Fla.) Fla.), 2006, Vol.31, p.T39-T39
Hauptverfasser: Kendziorra, Kai, Meyer, P., Wolf, H., Barthel, H., Hesse, S., Seese, A., Sorger, D., Patt, M., Becker, G., Schildan, A., Gertz, H.J., Sabri, O.
Format: Artikel
Sprache:eng
Schlagworte:
Alzheimer's disease
Brain
Cognitive ability
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Zusammenfassung:Objectives: For more than 20 years, post-mortem studies of the brains of those with Alzheimer's disease (AD) have consistently found damage or abnormalities in the nicotinic pathways projecting from the basal forebrain to cortical areas.
ISSN:1053-8119
1095-9572
DOI:10.1016/j.neuroimage.2006.04.029