Increased vesicular monoamine transporter binding during early abstinence from chronic methamphetamine abuse: Preliminary PET / (+)[ 11C]DTBZ findings

Increased vesicular monoamine transporter binding during early abstinence from chronic methamphetamine abuse: Preliminary PET / (+)[ 11C]DTBZ findings

Efforts to document striatal dopamine neuron damage in living brain of MA users have focused on the binding of (+)[11C]DTBZ (dihydrotetrabenazine), a vesicular monoamine transporter (VMAT2) PET radioligand, as a stable dopamine neuron biomarker.

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Bibliographische Detailangaben
Veröffentlicht in:NeuroImage (Orlando, Fla.) Fla.), 2008, Vol.41, p.T122-T122
Hauptverfasser: Boileau, Isabelle, Houle, S., Tong, J., Rusjan, P., Wilkins, D., Selby, P., Wilson, A.A., Kish, S.J.
Format: Artikel
Sprache:eng
Schlagworte:
Brain
Dopamine
Drug use
Psychopharmacology
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Zusammenfassung:Efforts to document striatal dopamine neuron damage in living brain of MA users have focused on the binding of (+)[11C]DTBZ (dihydrotetrabenazine), a vesicular monoamine transporter (VMAT2) PET radioligand, as a stable dopamine neuron biomarker.
ISSN:1053-8119
1095-9572
DOI:10.1016/j.neuroimage.2008.04.090