TCT-637 A Novel Bioactive and Coating-Free Stent Surface Exhibits a Reduction in Neointimal Hyperplasia by Decreasing Platelet Aggregation and Promoting Endothelialization

TCT-637 A Novel Bioactive and Coating-Free Stent Surface Exhibits a Reduction in Neointimal Hyperplasia by Decreasing Platelet Aggregation and Promoting Endothelialization

In-Vitro data indicate that those results may be related to a significant reduction of adherent platelets combined with enhanced neutrophil adhesion, which promote reendothelialization and decrease neointimal hyperplasia by locally regulating acute inflammatory response and endothelial recovery. [.....

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Veröffentlicht in:Journal of the American College of Cardiology 2012-10, Vol.60 (17), p.B185-B185
Hauptverfasser: Bailey, Lynn, Groothuis, Adam, Zucker, Arik, Buzzi, Stefano, Mäder, Armin, Ziogas, Algirdas, Milleret, Vincent, Ehrbar, Martin, Edelman, Elazer
Format: Artikel
Sprache:eng
Schlagworte:
Cardiology
Cardiovascular
Drug therapy
Internal Medicine
Microscopy
Stents
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Zusammenfassung:In-Vitro data indicate that those results may be related to a significant reduction of adherent platelets combined with enhanced neutrophil adhesion, which promote reendothelialization and decrease neointimal hyperplasia by locally regulating acute inflammatory response and endothelial recovery. [...]this novel approach may be an effective alternative to DES in reducing clinical in-stent restenosis.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2012.08.674