Platelet Function Monitoring in Patients With Coronary Artery Disease

Platelet Function Monitoring in Patients With Coronary Artery Disease Paul A. Gurbel, Richard C. Becker, Kenneth G. Mann, Steven R. Steinhubl, Alan D. Michelson Studies of patient responsiveness to antiplatelet therapies, particularly aspirin and clopidogrel, have increased dramatically in recent years. However, the relations of ex vivo measurements of platelet function to in vivo platelet reactivity and clinical outcomes remain largely unknown. This article discusses current methods of measuring platelet function in various clinical and research situations, their advantages and drawbacks, and their clinical and treatment implications.