Establishment of a Model to Objectively Examine Maximal Nasal Decongestion Using a Clinically Available Antihistamine/decongestant

Establishment of a Model to Objectively Examine Maximal Nasal Decongestion Using a Clinically Available Antihistamine/decongestant

Rationale Complete nasal allergen challenge (cNAC) with acoustic rhinometry represents a promising model to measure objective effects on allergen induced nasal congestion (AINC) with novel agents, using smaller sample sizes than symptom based efficacy studies.

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Veröffentlicht in:Journal of allergy and clinical immunology 2008-02, Vol.121 (2), p.S277-S277
Hauptverfasser: Romero, F.A, Phillips, P.G, Norris, V, Turner, K, Hutchinson, K, Allan, R.J, Tan, E.F, Misfeldt, J, Ward, J.K, Casale, T.B
Format: Artikel
Sprache:eng
Schlagworte:
Allergies
Allergy and Immunology
Drug therapy
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Zusammenfassung:Rationale Complete nasal allergen challenge (cNAC) with acoustic rhinometry represents a promising model to measure objective effects on allergen induced nasal congestion (AINC) with novel agents, using smaller sample sizes than symptom based efficacy studies.
ISSN:0091-6749
1097-6825
DOI:10.1016/j.jaci.2007.12.1095